Are there nonstop flights from Detroit (DTW) to Brussels (BRU)?

No. The fastest connection is via Dublin, about 8h 30m of total flying time.

What is the fastest connection from Detroit (DTW) to Brussels (BRU)?

via Dublin ≈ 8h 30m, via Toronto ≈ 8h 31m, via London ≈ 8h 32m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 47,000 JAL miles (economy, one way, based on the published award charts).

Detroit Metropolitan Wayne County Airport (DTW) to Brussels Airport (BRU)・6,380 km

No nonstop flights. The fastest connection is via Dublin (DUB), about 8h 30m of flying time (layover not included).

With milesANA 27,500 miles+ (via EWR)JAL 47,000 miles+ (via AMM)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

18 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.