Are there nonstop flights from Moscow (DME) to Porto (OPO)?

No. The fastest connection is via Istanbul, about 6h 40m of total flying time.

What is the fastest connection from Moscow (DME) to Porto (OPO)?

via Istanbul ≈ 6h 40m, via İzmir ≈ 7h 2m, via Tel Aviv ≈ 8h 45m (estimated flying time, excluding layovers).

Domodedovo International Airport (DME) to Francisco de Sá Carneiro Airport (OPO)・3,699 km

No nonstop flights. The fastest connection is via Istanbul (IST), about 6h 40m of flying time (layover not included).

None.

3 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.