Are there nonstop flights from Cancún (CUN) to Manzanillo (ZLO)?

No. The fastest connection is via Mexico City, about 3h 11m of total flying time.

What is the fastest connection from Cancún (CUN) to Manzanillo (ZLO)?

via Mexico City ≈ 3h 11m, via Mexico City ≈ 3h 12m, via Houston ≈ 4h 19m (estimated flying time, excluding layovers).

Cancún International Airport (CUN) to Playa de Oro International Airport (ZLO)・1,858 km

No nonstop flights. The fastest connection is via Mexico City (NLU), about 3h 11m of flying time (layover not included).

None.

4 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.