Are there nonstop flights from Rome (CIA) to Luton (LTN)?

No. The fastest connection is via Olbia, about 3h of total flying time.

What is the fastest connection from Rome (CIA) to Luton (LTN)?

via Olbia ≈ 3h, via Prague ≈ 3h 19m, via Bratislava ≈ 3h 29m (estimated flying time, excluding layovers).

Ciampino–G. B. Pastine International Airport (CIA) to London Luton Airport (LTN)・1,488 km

No nonstop flights. The fastest connection is via Olbia (OLB), about 3h of flying time (layover not included).

None.

14 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.