Are there nonstop flights from Cape Girardeau (CGI) to Chicago (ORD)?

Yes. Contour Airlines fly this route. Flight time is about 1h 9m.

Cape Girardeau → Chicago

Cape Girardeau Regional Airport (CGI) to Chicago O'Hare International Airport (ORD)・547 km

Nonstop flights available (1 airline). Flight time about 1h 9m. Nonstop return flights also operate.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.