Are there nonstop flights from São Paulo (CGH) to Santiago (SCL)?

No. The fastest connection is via Curitiba, about 4h 3m of total flying time.

What is the fastest connection from São Paulo (CGH) to Santiago (SCL)?

via Curitiba ≈ 4h 3m, via Foz do Iguaçu ≈ 4h 5m, via Florianópolis ≈ 4h 10m (estimated flying time, excluding layovers).

Congonhas–Deputado Freitas Nobre Airport (CGH) to Comodoro Arturo Merino Benítez International Airport (SCL)・2,587 km

No nonstop flights. The fastest connection is via Curitiba (CWB), about 4h 3m of flying time (layover not included).

None.

8 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.