Are there nonstop flights from Guangzhou (CAN) to Madrid (MAD)?

Yes. China Southern Airlines fly this route. Flight time is about 12h 42m.

What is the fastest connection from Guangzhou (CAN) to Madrid (MAD)?

via Chongqing ≈ 13h 12m, via Chengdu ≈ 13h 12m, via Budapest ≈ 13h 12m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 45,000 JAL miles (economy, one way, based on the published award charts).

Guangzhou Baiyun International Airport (CAN) to Adolfo Suárez Madrid–Barajas Airport (MAD)・10,375 km

Nonstop flights available (1 airline). Flight time about 12h 42m. Nonstop return flights also operate.

With milesANA 30,000 miles+ (via IST)JAL 45,000 miles+ (via HKG)Economy, one way, estimate. Tap a connection for miles by cabin.

35 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.