Are there nonstop flights from Buffalo (BUF) to São Paulo (GRU)?

No. The fastest connection is via Washington, about 10h 32m of total flying time.

What is the fastest connection from Buffalo (BUF) to São Paulo (GRU)?

via Washington ≈ 10h 32m, via Newark ≈ 10h 34m, via New York ≈ 10h 35m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 45,000 JAL miles (economy, one way, based on the published award charts).

Buffalo Niagara International Airport (BUF) to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU)・8,086 km

No nonstop flights. The fastest connection is via Washington (IAD), about 10h 32m of flying time (layover not included).

With milesANA 30,000 miles+ (via EWR)JAL 45,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

10 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.