Are there nonstop flights from Brussels (BRU) to Charlotte (CLT)?

No. The fastest connection is via New York, about 8h 56m of total flying time.

What is the fastest connection from Brussels (BRU) to Charlotte (CLT)?

via New York ≈ 8h 56m, via Dublin ≈ 8h 57m, via Newark ≈ 8h 57m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 40,000 JAL miles (economy, one way, based on the published award charts).

Brussels Airport (BRU) to Charlotte Douglas International Airport (CLT)・6,755 km

No nonstop flights. The fastest connection is via New York (JFK), about 8h 56m of flying time (layover not included).

With milesANA 27,500 miles+ (via EWR)JAL 40,000 miles+ (via LHR)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

15 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.