Are there nonstop flights from Bremen (BRE) to Valletta (MLA)?

No. The fastest connection is via Munich, about 3h 19m of total flying time.

What is the fastest connection from Bremen (BRE) to Valletta (MLA)?

via Munich ≈ 3h 19m, via Stuttgart ≈ 3h 19m, via Frankfurt am Main ≈ 3h 20m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Bremen Airport (BRE) to Malta International Airport (MLA)・1,964 km

No nonstop flights. The fastest connection is via Munich (MUC), about 3h 19m of flying time (layover not included).

With milesANA 15,000 miles+ (via MUC)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

12 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.