Are there nonstop flights from Boston (BOS) to Samos Island (SMI)?

No. The fastest connection is via Zurich, about 10h 14m of total flying time.

What is the fastest connection from Boston (BOS) to Samos Island (SMI)?

via Zurich ≈ 10h 14m, via Milan ≈ 10h 15m, via London ≈ 10h 15m (estimated flying time, excluding layovers).

from 27,500 ANA miles (economy, one way, based on the published award charts).

Boston Logan International Airport (BOS) to Samos Airport (SMI)・7,856 km

No nonstop flights. The fastest connection is via Zurich (ZRH), about 10h 14m of flying time (layover not included).

With milesANA 27,500 miles+ (via VIE)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

8 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.