Are there nonstop flights from Boston (BOS) to Prague (PRG)?

No. The fastest connection is via Amsterdam, about 8h 22m of total flying time.

What is the fastest connection from Boston (BOS) to Prague (PRG)?

via Amsterdam ≈ 8h 22m, via Dublin ≈ 8h 22m, via Edinburgh ≈ 8h 23m (estimated flying time, excluding layovers).

from 23,000 JAL miles, from 27,500 ANA miles (economy, one way, based on the published award charts).

Boston Logan International Airport (BOS) to Václav Havel Airport Prague (PRG)・6,251 km

No nonstop flights. The fastest connection is via Amsterdam (AMS), about 8h 22m of flying time (layover not included).

With milesJAL 23,000 miles+ (via LHR)ANA 27,500 miles+ (via FRA)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

26 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.