Are there nonstop flights from Barcelona (BCN) to Santa Cruz (VVI)?

Yes. Boliviana de Aviación fly this route. Flight time is about 11h 31m.

What is the fastest connection from Barcelona (BCN) to Santa Cruz (VVI)?

via Madrid ≈ 12h 3m, via São Paulo ≈ 13h 30m, via Bogota ≈ 14h 16m (estimated flying time, excluding layovers).

from 35,000 ANA miles (economy, one way, based on the published award charts).

Josep Tarradellas Barcelona-El Prat Airport (BCN) to Viru Viru International Airport (VVI)・9,369 km

Nonstop flights available (1 airline). Flight time about 11h 31m. Nonstop return flights also operate.

With milesANA 35,000 miles+ (via BOG)Economy, one way, estimate. Tap a connection for miles by cabin.

8 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.