Are there nonstop flights from Asyut (ATZ) to Madrid (MAD)?

No. The fastest connection is via Cairo, about 5h 21m of total flying time.

What is the fastest connection from Asyut (ATZ) to Madrid (MAD)?

via Cairo ≈ 5h 21m, via Amman ≈ 6h 8m, via Jeddah ≈ 7h 31m (estimated flying time, excluding layovers).

from 30,000 ANA miles (economy, one way, based on the published award charts).

Asyut International Airport (ATZ) to Adolfo Suárez Madrid–Barajas Airport (MAD)・3,500 km

No nonstop flights. The fastest connection is via Cairo (CAI), about 5h 21m of flying time (layover not included).

With milesANA 30,000 miles+ (via CAI)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

5 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.