Are there nonstop flights from Appleton (ATW) to London (LHR)?

No. The fastest connection is via Detroit, about 8h 41m of total flying time.

What is the fastest connection from Appleton (ATW) to London (LHR)?

via Detroit ≈ 8h 41m, via Chicago ≈ 8h 46m, via Newark ≈ 9h 1m (estimated flying time, excluding layovers).

from 27,500 ANA miles (economy, one way, based on the published award charts).

Appleton International Airport (ATW) to London Heathrow Airport (LHR)・6,213 km

No nonstop flights. The fastest connection is via Detroit (DTW), about 8h 41m of flying time (layover not included).

With milesANA 27,500 miles+ (via DEN)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

13 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.