Are there nonstop flights from Kayseri (ASR) to Madrid (MAD)?

No. The fastest connection is via Istanbul, about 4h 56m of total flying time.

What is the fastest connection from Kayseri (ASR) to Madrid (MAD)?

via Istanbul ≈ 4h 56m, via Istanbul ≈ 4h 56m, via İzmir ≈ 4h 57m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Kayseri Erkilet International Airport (ASR) to Adolfo Suárez Madrid–Barajas Airport (MAD)・3,324 km

No nonstop flights. The fastest connection is via Istanbul (SAW), about 4h 56m of flying time (layover not included).

With milesANA 15,000 miles+ (via IST)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

17 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.