Are there nonstop flights from Karpathos Island (AOK) to London (LHR)?

No. The fastest connection is via Venice, about 4h 19m of total flying time.

What is the fastest connection from Karpathos Island (AOK) to London (LHR)?

via Venice ≈ 4h 19m, via Athens ≈ 4h 19m, via Innsbruck ≈ 4h 20m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Karpathos Airport (AOK) to London Heathrow Airport (LHR)・2,826 km

No nonstop flights. The fastest connection is via Venice (VCE), about 4h 19m of flying time (layover not included).

With milesANA 15,000 miles+ (via VIE)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

16 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.