Are there nonstop flights from Amsterdam (AMS) to São Pedro (VXE)?

Yes. TUI fly Netherlands fly this route. Flight time is about 6h 4m.

What is the fastest connection from Amsterdam (AMS) to São Pedro (VXE)?

via Porto ≈ 6h 34m, via Nantes ≈ 6h 34m, via Lisbon ≈ 6h 34m (estimated flying time, excluding layovers).

from 30,000 ANA miles (economy, one way, based on the published award charts).

Amsterdam Airport Schiphol (AMS) to Cesaria Evora International Airport (VXE)・4,729 km

Nonstop flights available (1 airline). Flight time about 6h 4m. Nonstop return flights also operate.

With milesANA 30,000 miles+ (via LIS)Economy, one way, estimate. Tap a connection for miles by cabin.

10 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.