Are there nonstop flights from Buenos Aires (AEP) to Santa Fe (SFN)?

Yes. Aerolíneas Argentinas fly this route. Flight time is about 57m.

Buenos Aires → Santa Fe

Aeroparque Jorge Newbery (AEP) to Sauce Viejo Airport (SFN)・387 km

Nonstop flights available (1 airline). Flight time about 57m. Nonstop return flights also operate.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.