Are there nonstop flights from Buenos Aires (AEP) to Santiago del Estero (SDE)?

Yes. Aerolíneas Argentinas fly this route. Flight time is about 1h 36m.

Buenos Aires → Santiago del Estero

Aeroparque Jorge Newbery (AEP) to Vicecomodoro Angel D. La Paz Aragonés Airport (SDE)・940 km

Nonstop flights available (1 airline). Flight time about 1h 36m. Nonstop return flights also operate.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.